Breast specific gamma imaging


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Breast-specific gamma-imaging BSGIalso known as molecular breast imaging, is breast scintigraphy using a small-field-of-view gamma-camera and 99m Tc-sestamibi. There are many different types of breast cancer, and many have characteristics making them challenging to detect by mammography and ultrasound. BSGI is a cost-effective, highly sensitive and specific technique that complements other imaging modalities currently being used to identify malignant lesions in the breast.

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Breast Specific Gamma Imaging Supports Mammography

Scintimammography uses small amounts of radioactive material, a special camera and a computer to help investigate a breast abnormality. Scintimammography can detect cancer even when dense breast tissue and breast implants are present. It can reduce unnecessary procedures by helping determine whether a biopsy is needed.

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Breast-Specific Gamma Imaging

BSGI images the metabolic activity of breast lesions through radiotracer 99m-technetium sestamibi uptake. It uses a high resolution gamma camera to detect subcentimetre breast cancers even less than 5 mm. Breast cancer is identified based on the differential uptake of radiotracer in cancer cells as compared with normal surrounding breast tissue. This procedure provides an easy, rapid and economic way to perform supplemental breast imaging of women with dense breast tissue, cosmetic implants, post-surgical scars and masses, multiple suspicious lesions, and palpable lesions not detected by mammography and ultrasound.

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What is it? How it works: The short-lived radioactive agent 99mTc-sestamibi accumulates in cancer cells more than normal cells, allowing cancer to be seen on the basis of differences in metabolism. Starting about 5 minutes after intravenous injection of the radiotracer, each breast is gently stabilized between two detectors Figure MBIor between one detector and a compression paddle Figure